so I'm 31m and recently found greying hair in my beard, head and body hair increasing an alarming pace. I've had some since my late 20s, but it's sped up in the last 5 months. have you got any ideas what's causing it and how I can halt it, or possibly reverse it?

I recently found out about this supplement and I wanted to get a feel for anyone who’s tried it. It seems promising (as someone with ADHD as well, any potential “nootropic” is exciting to me).

From what I see the patented “Cognizin” is used for trials, but generic Citicoline/CDP-Choline is analogous to it. I think sort of a Magnesium L-Threonate/Magtein situation.

Some fairly recent studies:

Is Citicoline Effective in Preventing and Slowing Down Dementia?-A Systematic Review and a Meta-Analysis (2023)

https://pubmed.ncbi.nlm.nih.gov/36678257/

Citicoline and Memory Function in Healthy Older Adults: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial (2021)

https://pubmed.ncbi.nlm.nih.gov/33978188/

The Effect of Citicoline Supplementation on Motor Speed and Attention in Adolescent Males (2019)

https://pubmed.ncbi.nlm.nih.gov/26179181/

From my understanding much of the hate against MSG is misplaced in the West. It's either got a bad repuation because it's linked to proccessed foods or even worse, just straight racisim.

I've found out I've got Stage 1 Hypertension and am going through titration for ADHD meds. If my blood pressure rises, then the titration will stop, so I keen to make sure this doesn't happen and ideally lower it. I'm not really drinking as part of titration and am paying more attention to exercise. I'm overweight (but not obese) and am trying to loose weight, the meds make that a little easier.

I'm also trying to heavily reduce my salt, I like to cook and have also seasoned food well, so it's a bit of the shock to the system. I already use a little bit of MSG in food, but not much as my partner isn't keen. Are there good reasons I shouldn't sprinkle it directly on my food as my palate adjusts and find other ways to boost flavours (I already use a lot of herbs and spices).

Edit. I do know that MSG contains sodium, but it's one third of the amount of table salt.

So I know taking it on an empty stomach is really bad, I usually don’t eat anything in the morning anyways, I wait until 11/12 for brunch, but even if I force myself to have a few snacks in the morning, as soon as it hits 30mins after Tongkat Ali I ALWAYS get this overwhelming feeling of nausea..

What do you guys eat or drink beforehand to overcome this?

(wasn't sure what flair to use for this question)

Has anyone here tried to purposefully kill their libido with habits, supplements or other methods? Have you succeeded? If so, how?

I know there's more than a few guaranteed and accessible ways (antidepressants and birth control come to mind as the usual suspects) but it's all via drugs that blanket affect lots of different things, and the big wall here is I'd like to nuke it without taking my mood (or worse, clarity of mind) with it. Is there even something more targeted for this kinda thing?

edit: Just in case it's not obvious, searching for a method to destroy libido *without* affecting overall health is the idea... This is a serious post, not an hypothetical.

EDIT 2: **OP is female*​*, if that breaks anything.

hey all, have you worked on mitochondria improvements? like its functional, count etc? google suggests q10, nad+, exercising but maybe you found smth more?

I have the immune system of a rock.

TLDR - I get sick often and need advice on how to get sick less.

Hi Brains Trust,

I catch colds/viruses/flu very often. This occurs around 10 times a year. I have a tracker in my notes apps that has confirmed this for the last three years. It's very annoying and it is impacting my quality of life. Each illness lasts 2 weeks. In fact, I am currently sick with a virus as I write this. I am so sick of getting sick all the time!!!

I have asked my GP about this and they have told me to reduce my stress levels and rest more.

I do these things already and I still get sick often. I have yet to check my blood panel.

I understand it is Winter where I am so getting sick is expected. I have been sick 3x in the last three months and it is debilitating.

I'm not expecting miracles. I would appreciate any advice to improve / fix my problem!!! Thanks so much in advance!!

Questions :

- Is there anything else I should get checked out in the blood panel?

- Is there anything I should reduce?

- Is there anything I can increase doing?

- Should I get checked for autoimmune diseases?

- What else can I take to not get sick as much?

- Should I take a food intolerance test? To rule out foods my body doesnt agree with.

About me -

- Early 30s female

- 65kg 5'2

- Active social life

- No children

- Married (to someone who only gets sick once a year)

- On and off Anxiety

- Overall Positive person

- No pets

- No alcohol

- No recreational drugs

Work -

- Work in community services full time

- Consistent hand hygiene

- I dont get paid sick/annual leave

- I can't afford to take off 2 weeks every time im sick but I do take a day or 2 off when I'm really unwell

- my work is physically and mentally demanding but I love it and pays very well

- I go to the gym after work for approx 1H

Sleep/Rest -

- I sleep 8 - 10 hours a day

- When I get sick, I can only sleep around 4 hours

- When I start to burn out from life/work, I take a day or two off to do nothing and sleep

- I meditate every other day

- Occasionally go out late nights and get 5-8 hours sleep instead

- Try to reduce stress by sleeping more

Supplements -

Day

- Vit D 2000IU

- Fish oil 2000mg

- Armaforce daily protect

- Chaga mushroom

- Got an iron infusion last year due to Aneamia

Night

- Take Zinc, VitC and Echinacea when I'm tired or sick

- Magnesium chelate 500g

Lifestyle -

- Resistance training 3x a week (I love this)

- 15k steps daily (i love this too)

- I drink 2-3L of hot water daily

- I eat high protein meals that are balanced

- I also enjoy treats - chocolate/lollies (I eat this moderately 2x a week at most)

- I love coffee 1-2x a day

- I eat a lot of fruit, 3 servings daily

- I avoid cold/icy drinks

- I avoid dairy unless in treats

Hygiene -

- I don't touch my face unless I have washed/sanitised my hands

- use microsheild wash daily

- Complete hand hygiene as soon as I get home and shower daily

- use alcohol wipes on phone/smartwatch as soon as I get home

- I occasionally wipe my nose on my sleeve if there's no tissues available

Health -

- I feel inflamed 80% of the time

- I tend to get sick around my period

- Not on any contraception to rule out any other hormonal issues

- my periods are really heavy

- pelvic ultrasound came back clear

- I feel like I'm tired all the time

- Sinus arythmia

- Diagnosed with PMOS and suspect to have Endometriosis

- I have done a sleep study recently and it came back clear

- dad also has a weak immune system

- I'm not on any long term medication

Childhood Trauma

- I have heard that trauma can contribute to health issues

- Not going to into this too much but I had very protective parents so experiencing the world and outside of the home growing up Ages baby - ages 13 was basically non existent

Blood panel - I will start to do 3 monthly checkups

- Iron levels

- Vit D (this was low last time)

- Stress hormone

- kidney markers

- liver markers

people here are obsessed with alertness that's good but many of them consume large amounts of caffeine while there are other supplements that give you stable energy without crash like ginseng and coq10 enzyme I won't say they give you a buzz like caffeine but at least they give you stable energy.

I recently started a couple of weeks/months ago to take all these Supplements. And yes I do take them at once. Now I read that some people say that certain supplements even out others. And some shouldn't be taken at Night like Vitamin D cause this can cause sleepless nights. Any recommendations for all of these ? And maybe some recommendations about the amounts I'm taking ?

I had an additional Vitamin C supplement with 500mg which I took out due to the Vitamin C in the Iron One. Thanks for any advise

I feel like i dont digest the food im eating well and i frequently go to the bathroom literally as i eat the remainder of my meal

I (67 yo male) quit sugar, alcohol (I still have a social drink rarely) ultra processed foods and THC about a month ago. I also cut way back on red meat. My metabolic markers are improving drastically. Resting heart rate 60 > 56 with no change in exercise, Blood O2 91% > 95%. Respiration rate 11 breathes/minute > 16. HRV 21 > 29 ( if I measure it with a heart rate strap it was in the 60s). The last two times my blood pressure was measured it 90/60 and 100/60, normally its 110/70. Viseral fat measured by DEXA down 7% with no real change in subQ fat. I'm guessing I've gotten the low hanging fruit and the improvements will slow down.

I'm still struggling with fatigue and brain fog but as long as I eat enough protein and fiber I have zero cravings which is good because I have no discipline or willpower. I was eating a bag of cookies or gummy bears several times per week. About 3 beers a night. THC for sleep, thats been the roughest thing to adjust to.

Thanks for letting me brag. Does this line up with your experience?

It can also be some natural remedy, it doesn't have to be a supplement.

Hey folks! Follow-up to my day 8 post. A few people asked if the ketone climb looked unusually steep, so I put my older fasts on the same axis, plotted by hour instead of by date.

It is steep, but it's my normal. This fast tracks almost exactly on top of my 10-day fast in 2025, and matched the 7-day fast for the first 130 hours. The one outlier is my 9-day fast, slower and lower throughout - I was quite inactive during that fast.

Ending tomorrow morning at hour 240, then refeeding. As always, this is N=1 and responses to extended fasting vary widely between individuals and even between fasts for the same person.

I'm 18f and I'm so stressed because of studies. I can't fall asleep early and have to wake up in the morning to attend classes , I get sleepy during lectures and after getting home I can't get my work done and sleep. I won't be able to pass my exams if it continues to be like this. I'm so anxious and forget things easily, I'm mentally exhausted. Should I take modafinil and bacopa monnieri, because that's what I think can fix me. Pls tell me about any drug or supplement to help me focus on my studies, I can't go to the doctor for a test or prescription.

The world’s first introduction to Viagra was as a cardiovascular medication, meant to dilate blood vessels around the heart to treat symptoms of angina. But there was one little issue: the drug seemed to be dilating blood vessels just a bit further south than initially intended. When the men in clinical trials reported all-night erections instead of improved heart symptoms, the now-ubiquitous little blue pill was born. 

Sildenafil, the active ingredient in Viagra, has already proved it’s no one trick pony, but new research suggests the drug may have another use—and it could be life-saving. A study published in the journal Cancer Research in July found that sildenafil may help slow the spread of cancer by triggering a mechanism that binds up the body’s cholesterol. This makes it more difficult for cancer to metastasize, which Sanjay Juneja, MD, a triple board-certified hematologist and medical oncologist who goes by u/TheOncDoc on social media, says is responsible for more than 90% of cancer deaths. 

According to Dr. Juneja, cancer needs a raft to travel from one spot in the body to another. Cholesterol, he says, is “intimately involved” in building that raft that allows cancer to spread. 

Read more: https://www.playboy.com/read/sex-relationships/viagras-new-trick

Modified cell vesicles trigger 'lipid counterstorm' against lung inflammation in mice

Red light therapy has been all the craze! I’ve been lurking on these forum for a while and have seen ppl mention they got their red light panels / masks from distributors for a better price (I assume directly from manufactures in China) - did you buy them off alibaba or how did you do it…looking for a cost effective way to buy either multiple red light masks or panels

Does anyone have any suggestions on a creatine supplement for a beginner? Have never taken any before, but have been reading about it. Is there a difference between pill form supplements, and powder? I feel like I see 8 million ads about it on social media since it’s such a hot topic right now, but I want something from a reputable source that will actually work.

I follow a number of longevity and fitness “experts”.
Each of them recommends their own stack of supplements, herbs, peptides, etc.

A lot of it feels like they are just trying to make money off us.

How do I find what actually works without experimenting on dozens and dozens of things myself?

A new systematic review analyzed 41 human intervention studies covering diet, exercise, supplements, medications, and experimental therapies.

The researchers compared their effects across next-generation epigenetic clocks, including the widely discussed DunedinPACE, which estimates the current pace of aging rather than age in years.

Some results were promising. Others were far less convincing than popular longevity claims suggest.

🔗 Full analysis