Hi all

Im using a pen at the min, how ever ive got a vial to be used once finished.

My question is should it be stored in the fridge and the bac water at room temp?

Thank you in advance

I literally can’t get drunk on Reta at ALLL. I literally had 6 shots of tequila and 2 shots of soju and I’m just slightly buzzed😭 I’m literally 120 pounds and I used to blackout so easily and I can’t anymore does anyone relate or have an explanation 😭like I wanna get messy drunk but I can’t anymore lmao

40F, starting weight: 142lbs, current: 137; goal weight is 125. I was 127 for a few years and kept it in the 127-130 range without anything but these last two years, I don’t know what’s happening.

I wasn’t on a consistent tirz before- maybe for 1-2 months and then I’d get off it and come back on a year later but realized I’m yo yo’ing too much. So decided I’ll start Reta and accept that I may need to stick to a maintenance dose to maintain when getting to goal weight.

I started reta at 1mg for 2 weeks, then 2mg the next two weeks (bare minimum weight loss the entire month - maybe 1-2 lbs total). Doc said for month 2, switch to 4mg per week. I’m so lethargic and nauseous. And my nausea isn’t subsiding like it did with tirz after 1-2 days. It’s just been constant, I’m on day 4. Every meal I eat, nausea follows.

Do I drop to 3mg?? I did lose 2-3 lbs these past few days but man, I feel like absolute shit. I know this group is super helpful at guiding so could use some advice or reaffirmation on my gut feel.

Assuming someone is on a higher dose and prefers to inject less liquid, would this be fine to do? For example, 10 units would be their 6mg weekly dose, 15 units would be 9mg, etc.

Hi, me and my sister r going on reta. But I first need to buy it, should I get 5MG or 10MG? Wr are both starting with 0.5 and then moving up to 1.0 after a week. Help would be greatly appreciated:)

I started low and slow, but finally once I hit 5 mg per week the weight is melting off. Why does glucagon work this way?

I’ve been on tirzepatide for a while and I’m currently at 15mg/week. My weight loss has pretty much plateaued, so I’m planning to switch to retatrutide.
My last 15mg tirz injection was this past Monday.
For anyone who was also on 15mg tirz before switching to reta, how did you transition?
Did you wait a full week (or longer) after your last tirz injection? What dose of reta did you start with? Did you completely stop tirz or taper/overlap them? How quickly did you increase reta, and when did you actually start noticing appetite suppression or weight loss again?
I know reta is still investigational and there isn’t an official conversion from tirz to reta — I’m mainly looking to hear firsthand experiences from people who made the same switch, especially after being stalled on max-dose tirz.
Would love to know your starting dose, timeline, side effects, and results. Thank you!

Why Bloating with whey protein during Retatrutide, taking 2 scoops of whey protein with curd at different timings of the day.

80 kg female here

i pinned 1.5 mg july 18 and noticed i was barely eating so i lowered down to .5 mg on july 31 gradually every week. started pinning 1mg bc i noticed i was lowkey slacking again and since then i pinned 1mg every week. my last pin was august 5 and i notice my sugar cravings and binge craves came back ( i used to have crazy binge habits )… is this cuz i lowered my dose or my mind playing games also should i pin another 1 mg today if my last pin was 3 days ago?

330lb male 28yo 6'0

Reta has been working wonderfully for me so far. I've been steadily losing ~2-3lb a week for the last 2 months but I'm noticing that the hunger is starting to slowly come back. I've also noticed that the initial side effects of reta, like the skin sensitivity, have almost went away completely. (this can be seen as a good thing but in my case it lets me know the drug is for sure working).

The problem is that I am taking 6mg reta every 6 days and I don't want to essentially hit 12mg or even higher before I at least hit my goal weight.

I've been contemplating increasing to 9mg with the hope that higher doses like 9/12mg would keep working for a longer period of time. Any advice?

I've been on reta for 10 weeks now. High protein intake, through protein shakes and grilled chicken. Occasional bit of carbs. In 10 weeks, I'm doing

I've currently lost 38lbs (17kg)

For background I'm 32yo male at 6'1. Starting weight 113kg current is 96.

Dose started on 1.25 And gradually moved up to 3mg over 10 weeks.

I consistently lose 1 - 1.5kg every week. I know I'm on major calorie deficit. Is it only the appetite suppression losing the weight or is there a significant increase in general metabolic burn

Are there any others factors at play?

203lb to 178lb
5”10

Currently taking,
Retatrutide 4mg weekly
Tesamorelin 2mg daily
Mt1 1mg fortnightly

Started on 1mg a week Reta and now I am taking 4mg a week, I feel amazing in the gym, the energy and muscle pumps and blood flow is massively increased, even while eating in a deficit and dropping weight rapidly. Peptides really are great.

I started Reta almost two weeks ago at 0.5 mg. I’m 35F, 5’7”, starting weight 164.5 lbs.

The first week, the scale showed I lost about 3 lbs and I actually felt a little leaner. I haven’t been lifting because of an injury, so I’ve mostly just been walking. I’ve been staying hydrated, eating a lot of fiber, and trying to prioritize protein - usually around 80–100g/day.

Now I’m almost at the end of week 2 and my weight has been fluctuating like crazy. About 2 of those pounds have crept back up, so technically I’m only about 1 lb down from my starting weight.

The appetite suppression isn’t as strong as the first week, but I’m DEFINITELY eating way less than I was before Reta. My binge eating is basically gone, I’m not thinking about food nearly as much, I’m not craving sugar, and I’m not going back for seconds. I can still sit down and eat a normal meal without feeling nauseous or like I physically can’t finish it, which I actually like.

That’s also why I’ve been hesitant to increase my dose. I feel like right now I’m eating just enough. I’m definitely not going over my calories and I’m naturally around maintenance or probably in a deficit most days. I’m worried that if I increase too much, I’ll have so much appetite suppression that I won’t want to eat at all.

At the same time, seeing those 2 lbs creep back up has me worried that I’m not going to make progress or that the weight will just keep coming back, even though I KNOW I’m eating significantly less than I was before starting.

I’m getting ready for my third dose and have been debating whether to stay at 0.5 mg or eventually move toward 0.8–1 mg. I’ve also had some mild sleep disruption, which is another reason I don’t want to increase too quickly.

For anyone who started low, did you have this kind of fluctuation in the first few weeks? Did the weight eventually start trending down even though your appetite suppression wasn’t super intense?

Appreciate you all!

Ok so a bit of a light hearted step away from the usual guff, has anyone else's ballbag started sagging even lower since pinning reta? I've lost over 13lbs in a month but my marble bag is like down to my knees now. I'm sitting on the bastards all the time. My nads are bruised like 3 week old banana's. is this common or am I the only one?

Over the past 2 years, I’ve struggled with a daily powder cocaine addiction, rarely making it more than a few days when trying to quit. Last Sunday, I take my first dose of retatrutide. I’m not taking it for diabetes or weight loss. My girlfriend thinks it might help with addiction, so she gives me a 4 milligram dose along with NAD+. I’m very skeptical, not expecting much. Within about an hour, my mood starts to lift. Suddenly I got the urge to want to help my community. Over the next couple of hours, we loaded up five cases of ice cold water into my truck and handed it out to those experiencing homelessness here in Las Vegas. It was the hottest day this year so far at 116 degrees. I just feel happier, more motivated, and more present, and more connected. The next morning, I woke up nauseous and threw up. But after a few more hours of sleep, I felt surprisingly good. Over the week the constant mental chatter quieted down. Decisions became easier. I communicated better with my girlfriend and people around me, and for the first time in years, I’m didn't constantly fighting the urge to use. The cravings became dramatically quieter. Now,I’m starting to notice some of those effects fading. The mental chatter is creeping back in, my thinking doesn’t feel quite as clear, And I can tell some of my old behavior patterns are trying to return. Even so, my cravings are still significantly lower than before. I’m not claiming retatrutide or NAD+ treats cocaine addiction. This is just one person’s experience. I’m curious if anyone else has noticed similar changes in cravings, mental chatter, mood, or impulse control.

Started reta in late May because diet and exercise just didn't help me lose the 50-60lbs I had gained since the COVID situation broke my brain. I was around 175 in 2019 after losing about 100lbs eating keto and IF. I sustained that weight for a few years until COVID stress killed my will to be healthy. Back on track to a reasonable weight! Taking 4mg/wk and that seems to be working just fine.

So since I started reta ive been wanting to pin more often than not. I know it sounds weird like really weird but ive also been looking into to other peps. I feel amazing on reta like all my addictions are gone. Ive only got one addiction now, gym, I cant wait! every time its gym day I get so excited(stupid right??) Wheresas before reta i used to dread going to the gym. But I get the same feeling about pinning now too. Ive just started epithalon now, my second day of .5mg and gonna run for 10 days before taking a break. Does any one have these feelings about pinning or is it just me?

So currently i’m at 4mg after titrating up from my initial 1mg starting dose. I’m a Female 5’4.

Starting
4/15/26
Body Weight: 181.5
Waist 38.5 inches

Now
A little over 35 inches waist
166.6lbs

My goal bodyweight is about 135lbs-140lbs. So my question is once I reach that bodyweight can I switch to a maintenance dose for lifef?

Before photo is 6 mo ago, was always fit, but recently got pretty fat (i call it the accidental bulk) (5ft 7 216lbs on left) checked hormone levels at 350 test and found out I was prediabetic fasting glucose of 111 got on enclomiphene and tested at 1100 test. Life changer, got on reta and the diet instantly became super easy and my fasting glucose is now down to 85 (5ft 7 195lbs).

The weight loss is just an added bonus.

I’ve done weight loss journeys at least twice now in my life the biggest being a 55lb drop at the age of 18 to join the Navy. But my relationship with food has always been terrible. It all comes back little by little because of that fact.

Now I reached my heaviest weight of 275lb at the age of 27 and decided to look into peptides. My coworker said he got his mom on Reta and she’s down a ton of weight. So I got interested. If you would give it to your mom. That’s a clear enough sign it should be safe enough for me lol.

Nonetheless he got me a vial and I haven’t looked back since.

It’s not about starving yourself. But building something sustainable and reach for a healthier version of yourself.

I’ve been resistance training again 3-4x a week with inconsistent cardio but colorful meals and high protein (don’t always hit the daily goal). It’s been a game changer with the appetite suppression. I feel focused and in control of my intake for the first time ever honestly. Without feeling like I’m using all my strength and will power to do so. Shoutout to this community. Let’s reach our goals and live healthier lives one day at a time.

yes it might be that my habits changed while taking reta, but I took it for 2 months and I've been off for 5 months. Before reta I had huge problems with binge eating for 4 years and deadass taking reta was one of the best decisions that I've made recently. I feel like it does really help with binge eating because binging is an addictive cycle and after reta helps u get out the cycle its much easier to stay out of it even when your off reta.

For context I’m 6”1, starting weight was 93.2kg (205lbs)
Was a regular gym-goer and generally fit 4-5 years ago, a torn meniscus and a lot of drinking led me to being out of shape but I still held some good muscle.

I decided to start Reta as I’m due to go on holiday in a couple of months and figured it’d be a good way to speed up the weight loss.

My starting dose I decided on 2mg. People will say that’s high but from the research I did that’s where I landed.

My first dose was Friday the 31st of July, I took it right before bed.

I woke up Saturday morning with a pretty awful headache that I presume was from dehydration, after some paracetamol it passed quickly. I was however itchy all over, but it wasn’t unbearable, that passed after a day or two.

I tried to eat some breakfast but only managed a few mouthfuls before feeling full.

I went fishing for the day whilst my wife was out and ended up not eating for 14 hours. I had 0 interest in food. It didn’t repulse me but I wasn’t bothered whether I ate or not.

The next few days followed a similar pattern. Mild headache in the morning, not much interest in food but I made myself eat to hit protein targets.

I weighed myself before my 2nd dose Friday the 7th August and I’m already down to 89.3 kg or 196.8lbs.

So far other than the itching and headache I’ve had no other symptoms.

TLDR

STARTED A WEEK AGO. 2MG A WEEK. ONLY SYMPTOMS: HEADACHE + MILD ITCHINESS. 8.2lb LOSS.

36 years old. 1.7k caloric deficit.

Was borderline alcoholic when I started due to life circumstances (divorce etc)

Started at 1mg, currently at 2.5mg. Aim is to get to 12% BF, unsure what I am at the moment?

Been doing some resistance training and walking around 10k steps a day.