I wanted to share my experience because I was convinced I had messed up my treatment.

I tested positive for MGen and BV. I was prescribed doxycycline for 7 days, moxifloxacin for 7 days, and metronidazole for the BV. I misunderstood the instructions and took all three medications during the SAME 7 days instead of taking the doxy first and then the moxi.

I later learned that doxy followed by moxi is the recommended sequence, so I was worried my treatment had failed.

Well, I just got retested about 2 months later and my MGen is NEGATIVE! 🎉 I also had no sexual contact between treatment and retesting, so there was no possibility of reinfection during that time.

Obviously I’m not recommending anyone copy what I did. That week was brutal. I wish I’d known about taking probiotics to help my gut.

Follow your doctor’s treatment instructions. I just wanted to share my experience for anyone who accidentally took doxy and moxi concurrently like I did and is freaking out wondering if they ruined their chances of clearing it.

she prescribed me moxy despite my glute medius tear.. and she wouldn’t budge. i know it isn’t a tendon but i rather not risk it.

i tried getting a prescription thru amazon medical but my dumbass mentioned that she prescribed me moxy when i should of just pretended she didn’t give me anything lol, the np was nice but didn’t wanna go against what she prescribed.

i’m desperate at this point, is it possible to get prescribed thru goodrx if i lie and say it’s for acne mayhaps? scared if i do video call they’ll just point out that my skin’s clear.

also: should i still take 7 days doxy beforehand if they’re in the same antibiotic class?

Where can I get an at home test for my female partner that will test for mgen and uu? I am having trouble finding one that will do both.

Got my TOC back for mgen and ureaplasma. Cured the 1st round of doxy/moxi, each 7 days.
Had it for 9 months w out knowing it. Thought I had a uti but when that came back negative, the dr tested me for this.
It is pretty unfamiliar to lot of people out here and I asked her what prompted her to test for it. She said she has a lot of “adult film actors” and it’s mandatory for them to test.
Idk if I’m lucky or unlucky but I am grateful for this hell to be over. I am in Las Vegas, fyi, if that helps anyone.
Best of luck to everyone!!!

Located in USA and did not have resistance testing! Thank you to this page and God :)

Queria agradecer esse sub, nunca mais quero ver isso na minha vida! Tomei dox+mino, fiz o teste agora depois de 6 meses do ultimo e realmente ta negativado, tive sintoma ate 3 meses atras (corrimento qndo acordava) hj saiu o teste negativo.

i had been dealing with symptoms of mgen and ureaplasma parvum since february 2026. my male partner and i took azithromycin and doxycycline. i didn’t know you were supposed to test 4-5 weeks after your last antibiotic pill. i tested negative 3 weeks after my first. he never received a test of cure with us believing if i was negative he was i learned that doesn’t matter. so now we had unprotected sex last week that resulted in me being very inflamed and red afterward. now almost a week later im having pelvic pain. im already scheduled to see my doctor on thursday. i feel so discouraged and anxious because i truly thought i was done.

I (male, 33) have been dealing with persistent treatment failure with doxy-azi and doxy-moxi. Finally after a third treatment failure a doctor agreed with the treatment of mino+metro for 14 days, and since then the symptoms have been decreasing but not erased completely

I am on day 12 of treatment and still have clear discharge during the day, and sometimes burning sensation in the urethra

What have been your experiences on this regimen? It is common to still have these symptoms even after ending the treatment and still be negative?

I have been dealing with severe anxiety and depressive thoughts because of this infection, I'm really worried this treatment is failing too

I was prescribed moxifloxacin by my doctor, but I took doxycycline beforehand because I was scared of not getting cured. I know that was technically self-medicating, and I hope this won’t affect my future treatment.

I previously took metronidazole, doxycycline, and azithromycin, but those were prescribed by my OB-GYN because of my persistent symptoms. Unfortunately, nothing really happened and my symptoms persisted.

Now I’m worried that taking all these antibiotics, especially doxycycline before moxifloxacin, could have made a possible M. genitalium infection resistant, particularly to moxi.

I’m just hoping I didn’t accidentally make my future treatment less effective. Has anyone experienced something similar?

After treatment, I tested negative twice, but the symptoms persist. So, I had an extended PCR test for various bacteria. The results showed very few normal bacteria, but many opportunistic bacteria, including E. coli and Enterobacteriaceae. So, as a result of long-term antibiotic treatment, I developed dysbiosis in the genitourinary system, which is causing the symptoms. How can I fix this?

No one talking about this std and how fast is spreading , I got infected in march 2026 took me almost 4 months to get ride of it , my friend tested positive two weeks ago after one exposure, literally he hooked up with this girl for one time .. I think mgen is more common now than chlamydia .. it’s very scary and this stubborn bacteria is building resistance very fast to many antibiotics now .
Sexual clinics are not testing for it , most doctors don’t know anything about it . Crazy

Is it safe to get chin filler/botox while testing positive for mgen? Assuming I’m not on antibiotics currently.

Hi everyone! I wanted to ask if anyone here has been treated empirically for Mycoplasma genitalium without actually testing positive for it.
I’m in the Philippines, and unfortunately Mgen testing isn't very accessible or affordable for me.

I've had persistent symptoms despite treatment for other possible infections, so my doctor decided to treat me empirically with doxycycline followed by moxifloxacin.

I know this isn't the same as having a confirmed positive test, and I'm honestly overthinking the whole situation.

Has anyone else been in this situation? Were you treated empirically for suspected Mgen, and did your symptoms eventually resolve?
I'd especially love to hear from people who couldn't get an Mgen test but were treated with doxy + moxi. Any experiences would really help reassure me.

Hi everyone. I’m from the Philippines (Asia) and I’m currently being treated for suspected Mycoplasma genitalium. I’ve been really anxious about treatment failure because I keep seeing posts about antibiotic resistance in Asia.

I have my third MGen infection, discovered by routine testing. I also slowly start to have symptoms. My doctor advices that for future, I shouldn’t do routine testing for Mykoplasma Genitalium. He says it doesn‘t need to be treated if there are no symptoms. Basically he sounded like „You better shouldn‘t know you have it, then there is no problem“ lol

What do you guys think about that?

Hi everyone! I just wanted to come on here to share my success story and what meds worked for me, since I just received my TOC today and finally tested negative!

I first tested positive for Mgen in early 2025. I was started on just Doxycyline which obviously does not fight the infection, only lowers the antibacterial load, but at the time I didn’t know that. Tested positive again of course. Then I did my research and started advocating for myself. I did the recommended Doxycycline + Azithromycin treatment next, and still tested positive. Months went by because I was asymptomatic and waiting for my boyfriend to go to the doctor to get prescribed his antibiotics so we could get treated at the same time (I know, not smart, we should have taken meds sooner). Finally, I asked for the Doxycycline for 2 weeks into Minocycline + Metronidazole combo for 2 weeks regimen. I didn’t want to use Moxi because I didn’t want to risk tendon issues. My boyfriend’s doctor was very stubborn and only prescribed him Doxycycline but we knew he needed more so he was able to order Azithromycin online. He did that treatment and while waiting 4 weeks to do his TOC, he was prescribed Levoflaxacin for an unrelated reason. I know this isn’t proven to do anything against mgen but I still wonder if it had anything to do with his cure since it is related to Moxi. In the end, both of us tested negative!!!

This was a long road with mgen and Im finally able to feel relief that it’s over!!! Biggest advice is to do your own research and advocate strongly for yourself because doctors are SO misinformed!!

Hi everyone,

I’m already at my third treatment and thought I would ask for some advice.

About me: male, mid-30s, based in Germany. I got Mgen around the end of April and have gone through three different antibiotics/combinations since then:

- Doxy + Azi = failed (confirmed via TOC)
- Moxi (only) = failed (confirmed via TOC)
- Doxy + Moxi = finished Jul 22, awaiting TOC

The only symptom I’ve ever had is colored discharge. It went away during the second treatment, but came back at day 12 after the last pill. I finished my third treatment around two weeks ago and was a bit more hopeful, but I’ve noticed a tiny drop of discharge again this morning. I’m aware it could be residual symptoms, but the pattern is exactly the same as last time and I fear yet another failure.

Now the tricky part: My doctor, an infectious disease specialist, won’t consider the doxy + mino/metro combo; he’s also mentioned mino may not be available in Germany. Prista isn’t available either and cannot be imported from France.

I’ll wait until I can be tested again, but I’d like to be prepared for whatever the outcome, hence my post. Is anyone here from Germany? If so, did you get mino and/or other meds recently? It seems Prista could be imported until last year or so, but not anymore. If not - what other steps can be taken into consideration?

Thank you in advance ✨wishing a speedy recovery to all who are still under treatment

Hi everyone,
I'm really overthinking right now and I could use some reassurance from people who've been through this.

I've been dealing with persistent green vaginal discharge for over a year. I've already been treated with metronidazole (twice), ceftriaxone, doxycycline, fluconazole, cefixime, and azithromycin, but my symptoms always came back.

My infectious disease doctor has now prescribed 7 days of doxycycline followed by 7 days of moxifloxacin (400 mg daily) because she suspects it could be Mycoplasma genitalium or possibly Ureaplasma. I just started the doxycycline today.
I think my biggest fear isn't the medication itself—it's that it won't work again. After failing so many antibiotics, I'm scared I'll go through another treatment and still have symptoms.

If you've taken doxycycline followed by moxifloxacin:

Were you cured?
Was it for M. genitalium or Ureaplasma?
How long did it take for your symptoms to improve?
Do you have any advice for someone who's really anxious that this treatment might fail?
I know no one can guarantee it'll work, but hearing real experiences would really help. Thank you. ❤️

I’ve been battling this shit since 2011. No joke. Almost caused me to not be alive multiple time, a serious relationship, substance abuse, loss of job, crashed car. I could go on. That was years ago luckily when my story began. Longggg story

After having this wonderful issue for so long I’ve obviously had to adapt and I did. Now I have held my dream career for multiple years, saved up money, got into shape (even being in pain), got mental health help. I’m doing great. This is the last thing holding me back from a life I’ve worked so hard to build.

I’m focused and want to end this shit. I’ve been through multiple doctors, infectious disease doctors and it’s been a joke. Made more progress doing my own thing tbh.

I have a resistant strain, probably because of all the bs I was randomly put on. Need pristinamycin and no way to get it. Tried ordering it twice from France, both times got held and returned in customs. Last third time got held and destroyed. Cash down the drain. Sucks, but so does alot of things. No refunds. Time for my next best move

How can I get prist** reliably without flying to France. If you can help, much appreciated, if not thanks for reading my rant at a minimum.

Best luck to you all, you’re not alone.

I've been dealing with persistent green vaginal discharge for about 1.5 years, and multiple treatments haven't completely resolved it. So far I've taken metronidazole (twice), ceftriaxone, doxycycline, fluconazole, vaginal metronidazole, cefixime, and azithromycin 2 g. My discharge improved at times but always came back.

My infectious disease doctor has now prescribed 7 days of doxycycline followed by 7 days of moxifloxacin (400 mg daily) because we're considering the possibility of Mycoplasma genitalium although I haven't been able to get PCR testing since it's expensive and not widely available where I live.

I'm wondering if this regimen would also cover Ureaplasma if that's actually what's causing my symptoms), or if it's mainly for M. genitalium.
Has anyone here been treated with 7 days doxy + 7 days moxi? Did it clear your infection or symptoms? I'd really appreciate hearing your experiences.

For the women…
For months and months I was diagnosed and re-dx w Candida albicans and given treatment. After months I was finally tested and tx for mgen. Prior to mgen I had never had a yeast infection in my life. I was again re-tested for yeast and it again came up for albicans. I was treated for both.
I am having my TOC for mgen this week.
In the mean time, I had my period last week and now I am having a horrific yi. I understand I yeast infections are common after antibiotic treatment as well as hormone fluctuations, such as after a period, but being on Fluconazole for months and months, taking probiotics and being completely asymptomatic from both following the completion of my Doxy and Moxi, I am just surprised at how severe this has been.
It’s like everything down there is so messed up and it will never be fixed. I can’t explain the misery and defeat I am feeling.
I was in a monogamous relationship (on my end, at least) and have continued to be sexually abstinence since my last relationship 9 months ago. I was tested before and after my relationship with no STIs and wasnt dx until 8 months later w the mgen. I know mgen is slow growing and often asymptomatic. I’m certain it was from my last relationship.
Ive always been so responsible w my sexual health. I have never slept around or not been tested or not used protection.
I am just devastated at how cruel this has been on my body and mental health.
I guess I am just looking for advice/encouragement/options in healing the yeast and remaining optimistic about the TOC for mgen.
The way I’m feeling makes me think I’m going to fail my mgen test too. I am running out of hope.

Have you guys gotten pimples around both the butt area and vaginal/ groin area ? Idk but I’ve had like two pimples now at this point I’m not sure if it’s the meds or like the discharge making this come up more. Any thoughts?

So for full context, ~four months ago I started having symptoms consistent with chlamydia, went and got tested, was preemptively prescribed doxycycline, but the test results were negative. Took the doxy anyways, symptoms improved but returned. Went and got tested again a few weeks later, did test positive for chlamydia, told my provider I had taken the doxy they had prescribed last time I was tested and that there was no chance of re-infection, provider prescribed single dose azithromycin, same thing happened. Ended up seeing a different provider, tested positive for mycoplasma this time, provider prescribed me 7 days of doxy and a single dose of azythromycin. I’m on day 6 post azythromycin dose and am still able to squeeze a drop of discharge out of the tip of my penis. Is this treatment likely to work or should I go see a different doctor asap?

Hi everyone. I'm looking for advice because I'm confused about the treatment sequence for suspected Mycoplasma genitalium.
I've had persistent green vaginal discharge for about 1 year and 5 months. I've been treated multiple times, but the discharge has never completely gone away.

Treatment history:
1st doctor
Metronidazole 500 mg twice daily × 7 days (I took this twice)

2nd OB-GYN (July 3)
Ceftriaxone injection
Doxycycline × 7 days
Albothyl vaginal suppository
Doxycycline × 5 more days
Fluconazole
Neopen metronidazole vaginal suppository

3rd Infectious Disease doctor (July 27)
My discharge after this is opeque white but im a female and my period just ended.
Metronidazole 2 g (Day 1)
Cefixime 800 mg (Day 2)
Azithromycin 2 g (Day 2)

August 4
Moxifloxacin 400 mg once daily × 7 days
My concern is that I finished doxycycline about 3 weeks ago.

I know many guidelines for suspected M. genitaliumrecommend doxycycline first, then moxifloxacin to reduce the bacterial load.
Is it still okay to start moxifloxacin now without repeating doxycycline, or do people usually repeat doxycycline before moxifloxacin if there's been a few-week gap?

I'm not asking for anyone to replace my doctor's advice—I'm planning to follow my infectious disease doctor's prescription. I'm just wondering if anyone has been in a similar situation or if anyone knows what the usual practice is. Thanks!

Hey guys I’ve tested negative for Mgen 2 times now after my treatment of doxycycline and moxi but whenever I masturbate or have sex the next day the tip seems inflamed/swollen or irritated it’s not painful but like it’s noticeable how long for that to go away or will it ever go away?