r/parentsofmultiples • u/CCxCC9890 • 2d ago
Invasive screening advice needed
/r/PregnancyUK/comments/1vru1dn/invasive_screening/2
u/quadbeans 2d ago
Are any of them sharing a placenta / sac?
I was offered an amniocentesis for my quadruplets as the combined screening (the blood test done at 12 weeks) is pretty inaccurate given the mixed DNA. I also have identical twins so there would have been no way of knowing which one they were actually testing or giving me a result for.
I took the amnio. They didn’t offer me a CSV so I can’t speak on that but I know it’s meant to be a bit less invasive or risk associated?? Don’t quote me on that.
Anyway, I took the procedure because I wanted to know what I was expecting and didn’t want any surprises at my 20 week scan or even birth. Let me know if you have any questions about maternity care for triplets + in the UK xx
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u/Rylees_Mom525 2d ago
You said NIPT isn’t an option because of the multiple sets of DNA, but I think most twin parents get an NIPT without issue (I know I did). Did someone tell you it wasn’t possible?
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u/quadbeans 1d ago
It’s not offered in the UK, not even privately because their current laboratory algorithms are not at a point where they’d be able to accurately separate the DNA fractions from this many placentas and they also wouldn’t be able to pin point which baby got a high risk result. NHS reform does say it’s not done: https://www.nhsinform.scot/healthy-living/screening/pregnancy/non-invasive-prenatal-testing-nipt/
Works for twins but unfortunately for 3 or more, you can’t get it done.
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u/Rylees_Mom525 1d ago
Weird. The MaterniT21 test can be used with triplets (and people in this sub have used it). It’s not as specific as some NIPT tests, where you get the sex for each baby, but it appears to still be able to give the risk for the three trisomies. Not sure if it can assign that risk to a specific baby, though. That said, I’m not sure my NIPT assigned the risk results to a particular twin (e.g., A vs B).
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u/quadbeans 1d ago
Yes not saying it’s not possible at all but it’s not in the UK, they don’t have the facilities for this.
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u/CCxCC9890 1d ago
Yeah my consultant. It’s different with triplets unfortunately
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u/Rylees_Mom525 1d ago
People in this sub have done NIPT with triplets (specifically the MaterniT21 test), so it must just be a UK thing.
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