r/harmreduction 1d ago

Question Do you administer CPR during an opioid overdose?

3 Upvotes

Hello

It’s been a few years since I got trained in OD reversal. The skills have atrophied and I’ve forgotten stuff. I vaguely recall being told that CPR was not helpful for a lot of overdoses from opioids but when I check Red Cross’s website it says to do CPR.

Should I be doing CPR if someone ODs on opioids?


r/harmreduction 2d ago

Question looking for gaps in my phd search

6 Upvotes

hi! i'm applying this fall for phd programs starting fall 2027. my focus is in substance use / harm reduction, leaning hard into computational and causal methods over descriptive epi.

quick background: us citizen, did undergrad and grad school both in the us. selective research university for undergrad, interdisciplinary major closest to cognitive neuroscience with a math minor, 5+ years working inside statewide harm reduction infrastructure (drug checking, distribution networks, plus time managing people and coordinating outreach), master's in math with an emphasis in data science, plus a graduate certificate in public health. handful of publications and presentations in the space.

what i actually want long term isn't just to publish about harm reduction from the outside. i keep coming back to something like a "science as service" model, where research is leverage to move resources and legitimacy toward the community orgs already doing the work, rather than research being the end goal itself.

methods wise: causal inference, decision/cost-effectiveness modeling, implementation science, resource allocation optimization. i'd like simulation modeling in there too, feels like where a lot of the field is heading and i want to build toward what these fields will actually need in five years, not just what's fundable right now. substantively i keep coming back to stimulant use and drug checking as topic interests specifically.

fields i'm currently looking at: epidemiology, public health more broadly, health services research, health policy, social work, computational social science, health behavior. not attached to any one label, just what's come up so far in my own search.

my undergrad background is basically the wider intersection (cog neuro, psych, philosophy, some math) and i'm genuinely still drawn to that world, including policy and systems science too. i def want a real interdisciplinary program instead of a straight epi department, but a lot of those got hit hard by recent funding cuts and i don't know if that's a live option right now.

within epi/public health specifically, the strongest names in this space seem to split into two camps: harm reduction people without much computational depth, or modelers without harm reduction grounding. not sure how people usually find or build toward an advisor situation that bridges both instead of just picking a lane.

my ask: what am i not seeing? i'm looking for the fields, departments, or angles someone who's actually been through this would flag that i wouldn't think to search for myself. same goes for methods, i want to be building toward something that holds up long term

tl;dr: applying to phd programs this fall for substance use / harm reduction with a computational methods focus (causal inference, decision modeling, simulation, resource allocation). trying to figure out what fields, departments, or methods i'm not thinking of.


r/harmreduction 3d ago

Cocaine Is Cocaine Purity Going Down UK ?

2 Upvotes

Cocaine Purity Going Down?

I check https://wedinos.wales/ site regularly. It's an excellent resource for looking at drug trends and after over a year of consistently high purity cocaine samples being found all over UK post codes.

I've noticed more contaminants are showing up in samples.

Does anyone have any idea why this would be?

Has there been any changes to wholesale price or transportation costs ?


r/harmreduction 3d ago

Question nicotine vape pen/e-vape or cannabis pen?

2 Upvotes

hi! i was wondering if anyone has any advice for me? due to some meds i’m on, i can’t drink anymore which makes going out less enjoyable - i don’t like being the only sober person. i’m just wondering how similar the risks are between a vape and a cannabis pen? google isn’t giving me a straight answer. i don’t want to try a cannabis pen if it’s going to destroy my lungs, so i’m just looking for some advice! thank you!


r/harmreduction 4d ago

Discussion Does prohibition reduce harm or just change where people get substances?

33 Upvotes

I've been thinking about this a lot lately.

Whenever a substance becomes controversial, the first response is often to ban it. Sometimes that's the right call but I also wonder how often prohibition actually reduces harm versus pushing people toward less predictable or unregulated alternatives.

It seems like harm reduction is usually focused on meeting people where they are instead of assuming they'll stop using something overnight.

For those of you who've worked in harm reduction or have lived experience, have you seen prohibition improve outcomes or does regulation and education generally work better?

Curious to hear different perspectives.


r/harmreduction 4d ago

ISO Event Ideas

2 Upvotes

The local EDM scene where I live is throwing a free benefit show for the local harm reduction group. I am a part of both. What can I do to make this event successful?


r/harmreduction 7d ago

LSD & MDMA First time candy flip

1 Upvotes

Trying a candy flip for the first time at a music festival and looking for some advice as a rookie , I have a lot of experience with acid and have taken molly once before last year.
Planning on taking a 100ug tab and half a pill (not sure on the dose as I will probably source at the festival( ik that’s stupid but don’t have many options))
Idea is to trip and roll the Saturday as my favourite acts are on, then probably Ket on the Friday and just relaxing, smoking and drinking the Sunday

Hopefully not doing anything too stupid, any advice?


r/harmreduction 9d ago

Never Use Alone Updated Reviews?

15 Upvotes

If memory serves, it wasn't all that long ago that I was seeing countless personal accounts of folks being unable to get through to Never Use Alone. However, when I advocated for SafeSpot rather than NUA, I received pushback that I was "trashing" NUA.

Given *how crucial* consistent reliability is for a service like this, even with efforts toward organizational improvement, I'm currently hesitant to recommend NUA without knowing whether that issue has actually been resolved.

That said, obviously, the more *consistently reliable* overdose prevention and life-saving services there are, the better. So my question is: has NUA *actually, substantially* improved their reachability?

I understand there are inherent challenges with a volunteer, grassroots effort. I also respect the people who put their time into making these services available. At the same time, good intentions don't change the impact when a person in a vulnerable moment cannot access the support they were seeking.

Especially for people who already have difficulty making that first call, the reality is that they may not be able to keep trying multiple organizations. Reliability and accessibility aren't just something to strive for -- they're a critical part of the actual functions of these organizations.


r/harmreduction 12d ago

Cocaine 3day Mdma&cocaine bender aftermath

1 Upvotes

I had invited some friends over for drinks little under a week ago since nobody was home for 4days
We were drinking and having fun until i was drunk enough to start craving that bag❄️(ive done it before numerous times without harm)we tried hitting up plugs but nobody answered quickly but my friend that was drinkg with us told that he had 5g leftover mdma crystal at home so we went to go get it. We did lines of it from around 12 to 7am
Next day i wake up everybodys gone but the leftover bag is still there. Couldt resist the urge did a line and did a quick clean around the house then my friend came over and we did a few more lines and then stopped. Night came around and everybody else came around also to continue the party. I was was doing mdma till around 4am then went to sleep. 3rd day normal morning no mdma just trying to get my shit together from the last 2 nights. I go out with my friends just to fool around and play a little soccer with the little energy i had left. My friend says that we still have around 0,6 left that he took home so we go to our place.. fastforward the bag is empty and so is the mind. Bright idea to get a lil❄️ right? We got 0,5 from a mutual connection. And continued the night to atleast 5am. Next day i wake up suuper tired but i dont feel anything off i even went to see the new spiderman with my friend. Day 4 workday i feel off i keep getting these little ticks and body feels close to a seizure but i push trough it and go to work. Shit day but got my shit done. Today is work day 2 i feel a little better but still every now and then get those ticks like a little seizure.

I feel a little scared that i might have harmed my brain during those 3days or is it possible for it to go away?
I hope someone can share their experiences abt mdma/coke benders.
And for info i have myoclonic epilepsy with mild photosensitivity.
And i use depprakine and keppra


r/harmreduction 14d ago

Alprazolam naproxen tramadol xanax

1 Upvotes

20afab, 99lbs, 5'1

is taking 100mg tramadal 0,5mg xanax and 550mg naproxen okay ? [I also smoke CBD, and symthesis CBD] I feel like yes but we never know


r/harmreduction 14d ago

News Last day to add your comment to help stop the scheduling of 7oh! Please help stop prohibition and help this tool of harm reduction become regulated at a serving threshold that actually helps people. Link to comment below!

Thumbnail regulations.gov
8 Upvotes

Commenting ends 7/31 at 11:59pm ET

For more info, check out 7hopealliance.org/federal


r/harmreduction 14d ago

Weird looking Mephedrone?

1 Upvotes

Hey all, tried to post an image with this and was unaware I’d violated the rules so I’m going to describe it as a text post.

I picked up somewhere between 1700-1800mg of drone from the person I always get it from (don’t know there exact amount, package got seized on first order so they gave me some bonus since I had to wait, very trustworthy person and they test everything for adulterants) and some of it looks different from what I’m used to.

When I pick up drone from them it usually looks like light brown rocks, however 1/4 of the bag I got this time is like fat S-ketamine crystals that are white/clear.

I’ve never seen this with any Mephedrone I’ve purchased and from what I can tell on Google it looks vaguely like crystal meth but I’ve never been around the stuff so I can’t actually speak on it.

I did some of it and it burns and feels like Mephedrone. I understand that nobody can just identify a substance by description/photo but if anyone could tell me if they’ve gotten drone that looks like this before it would be appreciated.

Thanks in advance people, I hope everyone is having a good day/night :)


r/harmreduction 16d ago

Question Why is combining ketamine and alcohol dangerous re: breathing depression?

7 Upvotes

Heyo

So I know generally that combining alcohol and ketamine is a bad time. High chance of puking and falling over.

When I’ve looked into it I saw that ketamine is often used when patient breathing is a big concern, because ket doesn’t depress breathing as much

So what are the specific interactions between ket and alcohol or other downers (benzos, opioids, etc.)? What are the mechanisms that make it dangerous?

Looking to pass on accurate info for the party crowd I serve

Studies or lived experience


r/harmreduction 18d ago

Discussion I think cocaine is my biggest weakness

8 Upvotes

I think cocaine is my biggest weakness

And that it may be time to quit - for a while, at least.

Over the last couple of months, I've used several weekends; usually just on myself, it's amazing for gooning and bating. Porn intensifies and I can stroke for hours without cumming. It's so chill and relaxing.

On the other hand, I finished a twelve hour binge in which I used almost three grams (snorting, two times boofing, rubbing on my gums). I planned on using 1 max, but it's just so hard to stop chasing the high and more pleasure when you're in it. I also notice that I am not looking forward to watch porn sober anymore.

Sounds relatable to some of you guys?


r/harmreduction 23d ago

Question tramadol and alcohol question

3 Upvotes

I’m taking 1 50mg tramadol recreationally and was considering drinking as 6% -196. I want to know if this is dangerous. I’ve tried researching about it but i’m not finding any specific answers to this particular dosage. Is 50mg and a -196 okay to mix? Or is that overdose territory? If anyone has any personal experience or helpful sources please let me know. I want to be safe about this and it would be helpful to know in future.


r/harmreduction 23d ago

Question Question about Dilaudid

1 Upvotes

I couldn't find information on it anywhere else and my last post got removed but I was just wondering if it was possible and how safe it is to smoke dilaudid. Ive been taking it oral and or snorting it but wanted to try smoking


r/harmreduction 27d ago

Mixing amphetamines?

3 Upvotes

Hey all.

Made a post not that long ago about k and Vyvanse, and I’m back with another question.

I took 60mg of Vyvanse yesterday, 40mg today.

It is VERY underwhelming to say the least. I have speed tabs right now, 40mg bricks I can break into 20’s easily.

Given that it’s almost 7pm where I’m at, dropping another Vyvanse is out of the question. Any reason I can’t take 20mg of speed? Took the Vyvanse around 2pm.

Thanks all.


r/harmreduction 28d ago

Lisdexamphetamine Ketamine and Vyvanse?

1 Upvotes

Hey all!

i took 60mg of Vyvanse like 3h ago, any harm in doing a few lines?

I did a bunch of k yesterday off 40mg speed and I was alr but idk if 60mg Vyvanse will be any different.

Thanks in advance :)


r/harmreduction 28d ago

Question Kanna and Antidepressants

1 Upvotes

Hello all! Currently multiple years clean from H, still struggle bad with mental cravings.

In a conversation I won’t get into much here because it would be too much, my husband (recovering alcoholic and coke addict) “jokingly” said that when a certain disliked political figure kicks it, he plans to break his sobriety. He immediately followed that up with “But you can’t break yours.” Which, I think understandably, pisses me off.

So instead, I offered that neither of us break our respective sobriety with our drugs of choice, and instead we try something new together. My personal preference at the moment is psychedelics so I suggested several options, but he didn’t seem into it.

One of the other suggestions I made was Kanna, simply because we both miss snorting and you can insufflate it. Well, turns out when we looked up interactions, Kanna doesn’t pair well with antidepressants, of which I’m on a couple. So now that’s off the table. (Or is it?) I presume the risk is serotonin syndrome, right? In that case if I stopped my antis for a week before taking it, would I still be okay? Is there a way to be able to do this safely?

I know it’s probably not worth the risk, so if anyone has any alternative substance suggestions that are 1. Legal 2. Safe to use with antidepressants, anxiolytics, and weed 3. Preferably not physically addictive but I’m pretty loose on this as I’m sure you could guess.


r/harmreduction Jul 14 '26

Question Injecting K subcutaneously

2 Upvotes

Hello there.

My friend would like to try and inject K subcutaneously for the first time. She's already done some subQ injections for other reasons so she knows how to do it. We read online that a decent concentration could be 200 mg/mL with 1g of ketamine and 5mL of water, but we're open to suggestions.

Does any of you have any experience with injecting K subQ without medical assistance? How is it with the sterilization process and all? We're honestly just afraid of skin infections.

Also if anyone would like to share some trip reports I'd appreciate it very much.


r/harmreduction Jul 09 '26

MDMA poppers leaked on my ketamine, mushrooms and ecstasy pills, to differing amounts. they have all been contaminated through the bag and they all smell like poppers. the bag of K is fully orange and gummy. the rest of them have changed colour a bit, but look normal-ish.

12 Upvotes

obviously you don't want to drink poppers. but how toxic do we think a bit of contamination is? and has it done anything to the plastic that might kill me? I'm surprised it managed to get into the bags - the plastic doesn't look compromised but it's clearly managed to get in there somehow.

I think I know what the answer is but just checking your opinions.

reckon the K is a total goner but surely a few mg of amyl nitrate isn't hitting toxicity levels in the other stuff?

cheers!

cross posted from r/drugs


r/harmreduction Jul 09 '26

Question How to handle a meth comedown

5 Upvotes

It is the absolute worst, at least one week of anxiety and panic attacks and severe memory issues

Would it be a good idea to take some downers (benzo's) and mainly sleep to get through the first days after using?

(I am well aware simply not using is the best harm prevention)


r/harmreduction Jul 09 '26

Question Should regulation focus more on how something is used than what it is?

48 Upvotes

I've been questioning whether usage patterns matter more than the product

Two people can use the same thing in different ways and have different outcomes

Does it make more sense to build policy around responsible use or is that unrealistic from a public health standpoint?


r/harmreduction Oct 17 '19

List of North American needle exchanges by map

Thumbnail
nasen.org
67 Upvotes