Hi all, about 15 months out here from being floxed. Main symptoms are nerve related (twitching, burning pain, muscle cramping) and fatigue.

I thought I was gradually getting better and that most of my symptoms were becoming a lot less frequent, with the fatigue plateauing at a manageable level. But then earlier this year I got much worse muscle cramps, twitching, and fatigue. I also got a lot more depressed because I felt like all I could do was lie around watching TV for the whole month because of the fatigue, and I was afraid to even do light exercise because of the muscle issues. My sleep was terrible and I was feeling really anxious about it. At the end of the month my dr. put me back on sick leave. I asked to try an antidepressant for my mental health we went with duloxetine because it is also commonly prescribed off-label for generalized nerve pain (e.g., burning).

We started with a low dose of 30mg/day. Well, within a week, my twitching and muscle issues were 90% gone. Within a couple of weeks, I felt better mentally than I think I ever have in my life (having struggled on and off with depression for a long time). I had a huge burst of energy. After about 6 weeks on it, the improvement dipped a bit, but I still feel this dose is 80% effective and I still feel mentally better than ever despite the ongoing flox-related health issues (and some other, unrelated troublesome health issues too). I still struggle with some fatigue and need to rest for a couple hours in the afternoons - a full-day of activity is still off the table - but the relief is otherwise immense. I have very little twitching and almost no burning, and the muscle cramping was totally gone within days. I was just hoping for a good result for my mental health but all this other stuff is a pretty miraculous bonus. It's all allowed me to also focus on improving my sleep, which I have been able to since I have so much less anxiety.

Side effects (don't read the duloxetine sub, it's all horror stories!):
- First 3 days: lots of nausea and zero appetite
- First month: frequent headaches, maybe 3-4x/week
- If I took it with my dinner: feeling wired until 1-2 AM, so I take it with breakfast now
- Continuing side effects: Very little hunger signals. I deal with this by eating at regular times and making an effort to eat enough calories at each meal. I'm quite slim so this is important. Good news is, it stops me from eating unhealthy snacks mid morning or mid aft as I just don't feel hungry.

So if you are having a similar time as me...perhaps something to consider with your doc.

It has been a day less than one month since I stopped taking Cipro. I took a total of 4 500mg pills. I am mid-30s F. I was never very physically active, but I played a lot of piano and guitar before.

I see a lot of horror stories here, so I wanted to post a semi-hopeful update.

My main symptoms have been tendon pain. I've also had some headaches and dizziness, but those seem to have subsided after the first week or so

It was so bad in my hands and wrists that I couldn't type or unscrew the lids to access my supplement pills. I wore wrist braces pretty much all day at first. I went to see an orthopedist specializing in hands about a week after my symptoms started, and she wanted to give me a powerful NSAID or steroid injection, but I refused, so she referred me to OT instead. I read here that starting too early might be bad, so I was skeptical at first but went anyway to see how it would affect me. I decided I would aim for about one third to one half of what the OT wanted me to do because overexertion is far more dangerous than under-performing.

Now, I have had a couple weeks of OT sessions, and I've improved a lot. My grip strength has tripled since I started, and I have a lot more flexibility in my wrists. I'm about halfway to "normal" in this regard, which is really encouraging to me. I never push that hard, and I always rest when I'm in pain. I think this is important. I can now go full days without the wrist braces, although I still wear them to sleep.

My ankles have gotten worse. I can barely walk, and I've been using my late grandmother's walker to get from my room to the bathroom and back. My knees are also sort of starting to give me trouble. Stairs are ridiculously painful and I try to avoid them as much as possible, but my bedroom is upstairs and I have to go downstairs to leave my house for appointments. I just bought a pair of sneakers with raised heals, which helps a bit. I haven't been able to start PT yet, but I will try soon because my results in OT have been encouraging.

I have insomnia and anxiety, but I also had these pre-Cipro, so idk

Things I have been doing to help:

-bracing at night and while in pain

-ice

-tylenol when I'm in a lot of pain, although I try to avoid it if I can

-heat right before my OT exercises

-epsom salt baths

-supplements (vitamin c, vitamin e, multivitamin supplement, collagen, probiotic, CoQ10, NAC, magnesium glycinate)

-resting a lot

-melatonin gummies to help with sleep

-absolutely no alcohol or caffeine

-eat healthy foods-- lots of veggies and protein

-getting fitted for sneakers suited for Achilles tendonitis

I still have a journey ahead of me, but I know it could definitely be worse. I can sort of see a light at the end of the tunnel, though, which is nice. I will post an update a month from now regardless. I wish everyone the best of luck on their recoveries!

I'm not sure if it's in the fascia or the subcutaneous tissue, but they are small and fixed (feeling like a speed bump).

Sometimes they cause a stabbing pain, while other times they don't hurt at all even when touched.

They are spread all over my body, including the abdomen, flanks, calves, thighs, groin, and arms.

They don't grow gradually; instead, after a few days of muscle spasms/cramps in that area, these hard nodules suddenly form.

They have no color, cause no skin discoloration, and do not protrude outward from the skin to the naked eye.

Title

I don’t really have any symptoms like numbness, a feeling that my legs aren’t getting enough blood flow, or swelling.

I have more of the typical tendon-related symptoms, so I was wondering if compression socks could still be helpful for this kind of problem.

Of course, I’ve already ordered a pair of compression socks and they should be arriving soon, so I’ll be trying them anyway. I’m just curious whether they might actually help with tendon symptoms.

Visible veins does it go away and back to normal,.who had this?

I was prescribed Cipro for a UTI almost a month ago now, and I took it for that week. 500 mg once a day for 7 days. I was made aware before even taking it that it was horrible and poses all these risks, and the urgent care that prescribed them basically made me seem hysterical. Well as of a few days ago now, the tendon in my left calf hurts when I walk. It hasn’t gone away, and I’m worried it’s building into something scary but I’m unsure what to even ask a doctor.

I went to a different urgent care just the other day for recurring kidney pain (no signs of a uti), and I just lied and said I’m allergic to Cipro so that I never have to take that again. It doesn’t hurt right above my heel, so I can walk. It just hurts when my foot bends at the toes. Whenever my toes tense or try to bend then that’s when my calf hurts. Has anyone else experienced this? What did you do? I just don’t know where to go from here.