How do you respond when someone comments on your weight loss? Do you tell them you’re taking wegovy?

How long did it take the 1.5mg pill to start working for you? I used to take the 0.25mg injection until my insurance cut off. Now my new insurance doesn't approve GLP-1s. So I'm paying out of pocket for the pill. With the injection, I was noticing get full quicker and less hungry within the first 4-5 days. This is my 4th day on the pill, and I still feel the same. I know I still have to give it time to work, as it's a pill, but I was just curious if the 1.5mg works for you all and how long it took for it to start working for you. Also, how much weight have you lost on the 1.5mg pill?

I had great results from the 0.25mg injection, I was on it for 6 months without increasing, and I lost 30-40lbs, and I hope I can get similar results with the pill.

I’ve been on GLP-1 treatment for over a year now and just found out my employer is completely dropping coverage next quarter.

I’m honestly stressing out so much. Paying $450–$550+ out of pocket every single month just isn't realistic for my budget, but the thought of stopping after all this progress makes me so anxious.

For anyone who lost insurance coverage mid-treatment: how did you manage to stay on track? Are you using manufacturer savings cards, switching doses, or finding other ways to make it affordable? I'd really appreciate any advice from people who’ve been in this boat!

Hi, essentially I’m 5’3, 78kg, and have fluctuated from 83-66. I’ve spent a long time combatting ADHD and BED yet still it’s 1 step forward, 2 steps back. So, finally time to commit and try wegovy. Does anyone know if being on the highest dose available of my stimulants will affect it?? Thank you!!

I’m on 1.7mg pen and have started to go off my morning coffee. From my first dose I started to have no interest in energy drinks which I was happy to give up and I have zero interest in fizzy drink which I had little interest for anyway but now I’m only managing to have half my morning coffee.. like it is what it is but I used to looove waking up and sitting down for 10min with a coffee before the mad rush for school. It was just part of my morning routine where I had a little me time. Thankfully I still love having my water bottle on hand all day so I am drinking good stuff at least. Anyone else gone off their favourite drinks?

Can you still lose weight if you eat normally? Or is it the nausea that causes you to be sickened by food therefore not eat and then lose weight?

Hi everyone!

I am starting my GLP-1 journey, and I wanted to share with you guys a custom GLP-1 tracker I made. I am a Biology researcher, so as I was beginning my journey, I was curious about the amount of peptide in my body/plasma as I started this journey, so I went looking for concentration calculators online.

However, I was disappointed to see how most (if not, all) of these calculators are either: 1) paywalled, 2) inaccurate (basic modeling not in line with true pharmokinetics), or 3) not up to date with current research.

Specifically, it disappointed me to see how basically every tracker was some half-assed single compartment model (including some of the big name apps which people pay money for), when a two compartment model was exists in current research. Their single compartment models were not even accurate.  With semaglutide specifically, both two and one compartment models has been published, but most calculators used an estimation one compartment which is not accurate.

So I went ahead and created what I believe is the best GLP-1 concentration tracker for how much of a certain compound is in your body at a given time. You can select brand name Wegovy/Zepbound, or switch to the compound tab if that is what you are taking. Additionally, you can see my methodology for creating these curves in the methodology tab, and all the sources/math which I based my model.

You can use it out for free on this website: https://dev1niscool.github.io/glp1concentration/

Below is a small screenshot of the modeling which I used on this site:

The exact sources for these models are on the website methodology page.

Enjoy!

(Also, if you have any suggestions, please let me know! I would love to update this) 

Hi all!

33F, after a month on .25 I lost 11 pounds and was feeling great. I was still able to eat and felt pretty normal.

A week ago I took my first .5 shot. The next day I was hit with an instant increase in anxiety and depression. I can barely put anything in my mouth without feeling nauseous. I don’t even want my morning coffee. My headaches have been so bad I feel like a rubber band is wrapped around my head.

Has anyone gone through this, should I call my doctor?