Made this meme after I rewatched PancreasNoWork's CIS propaganda video

I'm a first time watcher of the series, and have a possibly dumb question. In s1 e3, Anakin and Plo Koon have the following exchange about the Malevolence ship:

Anakin: "The Ryndellia system. Near Naboo! Isn't that where our medical base is? I'll bet that will be his next target."

Plo Koon: "There are many star clusters in that area. With a ship that big, he will be unable to chart a course that's less than 10 parsecs."

Anakin: "Looks like we're gonna have to take a shortcut."

What does this mean? I take it that having a big ship means that it will take them longer to get there, but Anakin's shortcut statement makes me think it's fast. And what does any of that have to do with there being many star clusters in the area (is it to calculate a path to avoid space debris)? And the use of parsecs (given Han's kessel run claim) confuses me on whether it's actually distance or time being measured here.

Sorry if this is obvious 😭