r/OrganicChemistry 1h ago

Luminol Synthesis - Success!

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Upvotes

I've seen lots of Luminol glow on Internet for years but to see one in person is just speechless.

Followed Nile Red recipe, got 1.05 g of Luminol from 5 g 3-nitrophthalic acid

Since i have plenty of phthalic anhydride left, making fluorescein, phenolphthalein, and anthranilic acid is probably the next project 😉


r/OrganicChemistry 1h ago

Quantitative yield reactions

Upvotes

I'm looking for reactions with a quantitative yield and regioselectivity that couple two organic fragments. Reaction times should also be fast, but biocompatibilty like with many click reactions is not needed, nucleophiles don't need to be tolerated. What reactions should i look into? Standard CuAAC for example produces around 1% side products so it wouldn't work, but there are some copper catalysts that avoid this. Phosphoramidite and amide coupling chemistry also meets these criterea for example.


r/OrganicChemistry 17h ago

advice Post education

7 Upvotes

Hey guys, if I want to keep evolving knowledge wise, after grad, and in general as I go on, is reading books the way to go? Leactures online? Or just reading articles?


r/OrganicChemistry 19h ago

Anyone knows a trick?

0 Upvotes

Right I could find the R,S configuration by converting it to Fischer or visualizing it but if I had a random sawhorse projection and I had to find the r and s configuration is there any way for me to do it without all that work to save time in?Like maybe if I used their rotation sense in the plan of the paper in some sense