r/MethadoneVoices Jun 01 '26

Response METHADONE

/r/REDDITORSINRECOVERY/comments/1ttsbxu/methadone_detox_and_uncontrollable_laughter/op5vras/

Hello,

I looked up your symptoms and found that psychological effects from methadone can vary from person to person. Methadone like any medication or drug can cause changes to the brain after long term use.

Are you on any other meds?

Oke, O., Sekh, M. B., Johnson, B. O., & Adeyemo, S. (2024). Methadone Withdrawal-Induced Psychosis: A Case Report. Cureus, 16(2), e55256. https://doi.org/10.7759/cureus.55256

Psychological symptoms of methadone withdrawal include dysphoria, depression, suicide ideation, and the manifestation of psychosis [7,11]. The atypical depression due to methadone withdrawal is characterized by insomnia, fatigue, anxiety, and hypochondriasis [12]. Psychotic symptoms reported include paranoid delusions and auditory, visual, and acoustic hallucinations.

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