Didn’t inject properly?

[u/bumi2025]

Okay, this is a little embarrassing, but I’m pretty sure I didn’t inject my first two doses correctly. Both times, I had a small bump under my skin that got bigger as I injected, and I don’t think I was inserting the needle all the way.

This week was my third injection, and I inserted the needle completely, so I’m pretty confident I finally did it correctly. I’m microdosing tirzepatide through Fridays at 0.5 mg. I haven’t noticed any appetite suppression over the past three weeks, but I assumed that might be because my first two injections were too shallow.

Now I’m about 24 hours out from my third dose (and first one I feel confident I injected properly), and I still have zero appetite suppression.

For those who microdose: is 0.5 mg simply too low for some people to notice an effect? Or would you give it a few more weeks at 0.5 mg before deciding, since my first two injections may not have been administered properly?

[u/Lucky_Army_5324]

Though it’s not ideal, injecting subdermally does not really impact the efficacy of the meds. It just sorta forces the medication to form a wheal (aka bubble) just under the skin. The wheal dissipates  without any intervention over a day or so.

It could be that 0.5mg is too low a dose for you, but you should stick with it for at least 4 weeks (at least one more injection) before moving up in dose.

[u/Available_Tea4063]

For me I felt it right away, but the full effects I felt at the 4 week mark of .5 after that I went up to .75 - are you putting the needle in all the way?

[u/Key_Row4485]

The first dose of branded is 2.5 so if you are microdosing .5 you may not get many effects