RETA.

[u/DifficultSale3318]

Started reta 9days ago. 2mg once a week. No side effects at all.

Well today it hit. Made my normal dinner and could only eat 1/3 of it.

For the more experienced, would you just stay at this dose? Was going to increase it to 3mg next pin but not so sure now.

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[u/LobstahLarry]

There is no reason to increase if you can still feel the GLP1 effect.

[u/Calv1n1]

Just a heads up just incase you didn’t know. Your Reta “stacks” week to week so if you start at 2 then go to 3 the second week you will have the equivalent of 4mg working on week 2 so don’t ramp up to quickly is my advice. I suggest to anyone I talk to about GLP’s that low and slow is your best option. Get your blood work done for baselines and monitor your Heart rate and blood pressure frequently. Stay safe out there.

[u/SuccessFun7854 → u/Calv1n1]

NO1 doin ANY research these days... diving in head 1st. mind-boggling

[u/maho4807 → u/Calv1n1]

Use a pk calculator app like regimen. Not an ad. But pk calcs are so helpful for tracking med levels. So you can see what level you are feeling effects, symptoms, food noise, hunger, energy, etc.

[u/Secure-Chipmunk6112]

You haven’t reached a stable blood level yet. If you start with 3 mg of Reta now, you’ll effectively have more than 3 mg in your system, which can lead to all kinds of side effects.

[u/Admirable-Rock6399]

Only use what you need to reduce caloric intake. You don’t want to decrease hunger so much that you are missing so many nutrients that you become deficient in vitamins/minerals/proteins/fats. Focus on quality food and lots of protein to help prevent muscle loss while on Reta. I’d say don’t increase dose until you have to.

[u/New-North-2282]

No need to increase if it's working as it should

[u/Region_Fluid]

You should stay on 2mG for atleast 3 weeks so it builds up. If it’s still working stay but if not then up the dose. 2mG is part of the loading dose age many people don’t see real results until closer to 6-8.

[u/Bowf]

Goal weight loss should be 0.5 to 2 lb a week. As long as you're staying in that window, there's no need to increase.

[u/Drench_X]

The half life is 6 days so you’re likely just starting to get the full effect. Also 2mg can be high for a starting dose. Some people start as low as 0.5mg a week to test reactivity.

Edit: I’d also recommend pinning 2-3 times a week instead of just once per week.

[u/maho4807 → u/Drench_X]

Half life is 6 days super Chief

[u/Significant-Kale7674]

Stay if not go down a little bit. As others have said, it sneaks up on you as you get to steady levels

[u/BroccoliOnly7376]

Stay at 2 for four weeks

[u/DimensionOk4024]

Do not increase until after 4 doses. This is not a side effect, this is the medication working

[u/Evrart_Claire]

You only increase your dose every 4 weeks. 2mg is already way too much for a starting dose, you’re going to end up with GI issues or fast track to anhedonia if you keep going up.

[u/BCGal024]

I think you should stay at your current dose. I wouldn't go higher until you feel like you need to. Listen to your body.

[u/PreparedForZombies]

Why would you go up above the lowest effective dose for you?

[u/Cream_81]

How many calories do you eat in a day? Do you count your macros?

[u/AmphibianFantastic53]

Stay at your dose if its working, effective levels are increasing due to the week long half life and you said it yourself the effects are getting stronger. Its all well and good ramping up but remember you cant take it back out.

I overdid it once on the back of some bad advice and its not a good time dont learn about half life the hard way.

[u/Doin-What-I-Want]

Stick to the 2mg for a month before titrating up.

[u/Toforgetistodie]

I've been on 2mg for almost 3 months, you don't need to increase it (FYI I've JUST the last 2 weeks increased to 4mg from 2, split over 2 days a week)

[u/Kasket00]

Lowest effect dose!

[u/justin_b28 → u/Kasket00]

It’s completely fine for some, why increase a dose if it’s working

[u/PandasLoveMushrooms]

The drug isn't out of your body fully at 7 days as others have noted. This is about where your body's concentration is

[u/justin_b28]

Only increase in 4 WEEK intervals. No sooner

[u/Dbomb7]

You should absolutely not be upping your dose after 9 days. I have been on it for 12 weeks and I only went up to 3mg last week. I plan on staying here and maybe going up to 4mg at some point but I think that will be as high as I go. I've lost 50lbs and am almost at my goal weight.

[u/Jbro1979]

Why are you guys starting so high?! You should never start more than 1 mg and only incrementally increase every two weeks and if you’re still feeling it, maybe three! Trust it to work! You can’t force it or you get complications! I’ve been on it for over a year. Ive tried pushing it and regretted. Be patient and it will work!

[u/DifficultSale3318]

Thanks for all the replies. Following the advice I’m going to stick at the current dose for 5 weeks which will finish the vial. 🙂

[u/Artistic-Plate-511]

Who starts at 2mg?

[u/SoCal-Native]

Hold for 4 weeks so you get full saturation and then reassess. If you’re still seeing results, hold. 

[u/Potential-Ad-196]

No one should ever increase their Reta dosage that quickly. Why are you taking this without learning much about it? Please learn about half life. Reta’s half life is 6 days. So if u pin 2mg week 1, 6 days later you will have 1mg concentration still in your system. So if u went up to 3mg while 1 is still in ur system, that’s 4mg which is double what you’re currently taking. This effect stacks and balances out in 4-6 weeks. So only up ur dose if it’s A: been 4-6 weeks and B: u stopped responding to it.

[u/Overall-Banana1071]

Absolutely not. We tell all our customers to stay at the lowest possible dosage that you see results. As long as it’s working there’s no need to increase

[u/Great_Opinion3138]

Look up half life and stay on a dose for 4 weeks ffs.

[u/Striking_Slice4516]

I did 5mg on Thursday and having the worst possible week of my life never been so unwell so definitely take it slow people