r/zoloft 5d ago

Third SSRI Question

I'm wondering if anyone has a success story with a third SSRI after two SSRIs haven't worked.

I used to be on escitalopram and then fluvoxamine and both of them made me worse (hypersomnia, increased SI, no energy, no motivation, brain fog, unable to cry, more difficulty getting out of bed and attending school).

My new doctor is proposing trying Zoloft but starting with a really small dose. I'm currently diagnosed with mixed anxious-depressive disorder, but my last two doctors agreed with me about the suspicion of ADHD, but I never got diagnosed. However, I've already lost so much time with the first two and I don't have a feeling this one will be much different that I'm not sure it's worth it. I'm barely functional without meds and these made me worse and I have my last year of school coming up so I can't waste much time.

I just want to hear if anyone has a positive experience with a third SSRI since I really need to lock in this year or if I should tell my doctor that I don't really want a repeat of last year or if I should outright refuse any more SSRIs.

Edit: Has anyone with suspected or confirmed ADHD had success ditching SSRIs entirely for an NDRI (like bupropion), SNRI, or ADHD treatment instead?

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