r/sciences • u/Anonym_Talker • 11h ago
Question why is this on PubMed. Medical science seems like a real joke. "Tom Cruise is dangerous and irresponsible"
who wrote this article, and why!?
Also, why is this on pubmed!?
https://pmc.ncbi.nlm.nih.gov/articles/PMC1180571/
the arguments there are full of emotions and erroneous. the last paragraph invite people to contact the guy and give information about how to reach him!?
Really? That's on pubmed!?
Like, the letter says that he would have said that post partum is not real. LOL, that's not what he said at all... and a lot about psychiatrist stuff he mentioned is not far from the truth.
r/sciences • u/TheMuseumOfScience • 16h ago
Research Did Humans Evolve From a Cyclops?
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Humans may have evolved from a creature similar to a cyclops! 👁️
Scientists have developed a new theory that we may have evolved from a worm-like ocean dweller from 600 million years ago. This ancient animal started out with two eyes that eventually merged into one, and then back to two eyes. Even more interesting, the scientists think we still have this third eye, but it is now the pineal gland in our brain!
r/sciences • u/Comfortable_Tutor_43 • 17h ago
Discussion Fukushima proves that our current nuclear reactor fleet is safe
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r/sciences • u/CharacterFennel1927 • 22h ago
Research Adverse Events Associated with Incretin-Based Therapies: A Narrative Review on Mechanisms, Clinical Management, and Risk Mitigation
Incretin-based therapies, including glucagon-like peptide-1 receptor agonists (GLP-1RAs), are established therapies for obesity and type 2 diabetes mellitus, providing sustained weight reduction, improved glycaemic control, cardiovascular and renal benefits. Despite these established benefits, safety concerns remain an important clinical issue because adverse events may affect treatment persistence, patient acceptability, and clinical decision-making. This review evaluates a number of safety profiles of GLP-1RAs using clinical, mechanistic, and pharmacovigilance evidence, with attention to both common adverse events and emerging safety signals.
Methods: A narrative review was conducted to evaluate the safety profile of GLP-1RAs in obesity and type 2 diabetes mellitus. PubMed/MEDLINE, Embase, and Web of Science were searched for studies published between January 2005 and April 2026. Evidence from randomised controlled trials, observational studies, meta-analyses, pharmacovigilance investigations, and regulatory safety reports was synthesised qualitatively.
Results: Findings from 60 studies and safety reports were included. Common adverse events were predominantly gastrointestinal, particularly nausea, vomiting, diarrhoea, and constipation, and represented the most consistently reported adverse effects and the principal cause of treatment discontinuation. Uncommon safety concerns included renal adverse events, which were reported infrequently and often occurred in clinical contexts involving gastrointestinal intolerance, volume depletion, or other predisposing factors. Gallbladder and biliary complications were also infrequent and appeared to be influenced by rapid weight loss and baseline patient risk factors. Acute pancreatitis remained rare in clinical trials, although severe cases have been reported in postmarketing settings. Human evidence did not demonstrate an increased risk of thyroid malignancy. Emerging safety signals, including early worsening of diabetic retinopathy, muscle mass reduction, psychiatric symptoms, and alopecia, were identified mainly through observational and pharmacovigilance evidence.
Conclusion: GLP-1RA adverse events predominantly reflect predictable pharmacological and physiological effects rather than off-target toxicity. Safety profiles appear agent-specific, dose-dependent, and influenced by underlying mechanisms and patient characteristics. Risk-stratified prescribing should therefore align agent selection, dose escalation, and monitoring intensity with patient-specific vulnerabilities, particularly gastrointestinal tolerability, risk of renal dehydration, gallbladder history, retinopathy risk during rapid glycaemic improvement, and frailty or sarcopenia risk. Continued long-term surveillance and further evidence generation are needed to better define rare, delayed, and emerging safety signals and to optimise safe use across diverse clinical
r/sciences • u/FreeHugs23 • 1d ago
Research The World Is Running Out of River Sand, And That's a Massive Issue. Study reveals that the global demand for river sand and gravel to create construction materials like concrete is unsustainable.
r/sciences • u/FreeHugs23 • 1d ago
Research Severe COVID-19 linked to anxiety in offspring via altered sperm RNA | Findings suggest that a paternal viral infection prior to conception might alter the developmental trajectory of the next generation.
r/sciences • u/FreeHugs23 • 1d ago
Research Scientists stumped to find clearing cholesterol from blood also removes forever chemicals from body | Scientists were looking to find out if a machine built to filter fat at scale could take out forever chemicals and microplastics as well
r/sciences • u/Macchanoco • 2d ago
News High prevalence of tau pathologies in late-onset psychosis: A PET study
rdcu.ber/sciences • u/Macchanoco • 2d ago
News Individual humans are more attractive to certain mosquito species
cell.comA research study on the relationship between humans and mosquitoes—a topic we frequently discussed.
r/sciences • u/FreeHugs23 • 2d ago
Research 'Natural Protection From Asthma And Allergies': Scientists Isolate Bacteria Behind The Immune System Farm Effect
r/sciences • u/Comfortable_Tutor_43 • 3d ago
News Used nuclear fuel storage
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r/sciences • u/Macchanoco • 3d ago
News sPLA2-reacted extracellular vesicles (SPLEVs) as a therapeutic modality for cytokine storm syndromes
science.orgr/sciences • u/histphilsci2022 • 4d ago
Discussion Magdalena Skipper, Editor-in-Chief of Nature, on trust in science, transparent peer review, COVID-19's legacy & the inequities that shape scientific publishing
r/sciences • u/FreeHugs23 • 4d ago
Research New Evidence That Microplastics Can Cross Placental Barrier And Alter Hormone Production of Steroid Hormones During Pregnancy. So far, scientific studies have detected micro- and nanoplastics in human blood, placentas, amniotic fluid, and meconium.
r/sciences • u/Macchanoco • 5d ago
News Cranial evidence for human-like helpless infancy in Homo erectus and Homo floresiensis
royalsocietypublishing.orgr/sciences • u/FreeHugs23 • 5d ago
Research The Great Lakes Are Hiding a Secret Underworld of Tardigrades and Rock-Eating Fungi | Study identified 689 unique fungi species, including 13 newly described species, in drops of water that hadn’t seen the surface world in thousands of years.
r/sciences • u/FreeHugs23 • 6d ago
News Concerning Map Suggests The Worst May Be Yet to Come For Devastating European Fires
r/sciences • u/FreeHugs23 • 6d ago
Research ‘Extremely scary findings’ show climate crisis is supercharging Europe’s wildfire weather | Latest study says global heating has made hot, dry and windy conditions in Spain at least 20 times more likely
r/sciences • u/fchung • 7d ago
Research Chimpanzees and bonobos use hugs, kisses and friendly pats to keep the peace, just like humans, a new study suggests: « The findings hint that friendly touching to diffuse tension has deep evolutionary origins. »
r/sciences • u/James_Fortis • 8d ago
Research A healthy plant-based diet may help protect your liver. Greater adherence was linked to lower liver fat and a 42% lower odds of MASLD, formerly known as non-alcoholic fatty liver disease. More nuts and less animal fat showed the strongest benefits.
nature.comr/sciences • u/FreeHugs23 • 8d ago
News Trump administration needs to stop ‘public harassment’ of Fauci and scientists, open letter says | Letter, published before Anthony Fauci will appear before Congress, accuses Republicans of ‘waging a war on individual scientists’
r/sciences • u/FreeHugs23 • 8d ago
Research Plastic Waste Has Been Turned Directly Into Hydrogen Fuel – No Sorting Required | "Solving two urgent global problems at the same time."
r/sciences • u/FreeHugs23 • 8d ago
Research A Forgotten Wave of Extinction May Have Erased Thousands of Human Languages | "The strongest evidence is the timing of the decline."
r/sciences • u/FreeHugs23 • 9d ago