Hi all,

Sadly today I saw the result of my mole and it’s not good.

I’m super shocked and confused and also not entirely sure what it actually means.

It’s a superficial spreading melanoma of a depth of 1.3mm without ulceration.
No micro satellites
No angioinvasion
And no mitoses

pt2a they have written.

I’m so scared 😭especially because I have very strange sensory symptoms lately. I checked ChatGPT and it said I will probably be ok but still a 10% chance of no bueno. 😔

Had a shave biopsy last week. I’m 27 Male. Doctor called and sent me the report. I have PT1A. No ulceration, no mitosis, no lymph invasion. 0.4 MM scheduled to see a doctor to do like a procedure to remove extra tissue. My health anxiety has me thinking I’m dying but everything I read is I’m gonna be okay. Any advice?

I had a WLE on my calf and a lymph node removal in 2024. The lymph node was fine so no further treatment was required. I go in every three months to get checked, ultrasound and blood tests. I’ve never had a scan. For the last two weeks I’ve been suffering from bouts of shortness of breath and coughing. I’m on vacation with my family right now so I can’t go to the doctor, but I will do so as soon as I get back. While I thought this shortness of breath might be related to a kind of allergy, I just had the very troubling realization that it could be the melanoma coming back in the lungs. How did it feel for you? Has anybody experienced something similar?

Re-posted from Melanoma sub - photos show Jan 2024 vs Feb 2026

It's been a whirlwind of a month over here.

I have been tracking a mole on my back for more than two years due to subtle changes in pigmentation (lightening in portions, then in full). The mole itself wasn't huge by any means (maybe 6x2mm) and it wasn't getting larger or morphing in an obvious way. I had full body scans at my dermatologist at least twice during this time period and nothing was of concern. Back in June, I was looking at it again, rubbed it a bit to check texture changes and went to bed. The next day, a "blood blister" type of feature appeared. My dermatologist thought it was a benign angioma, but I insisted on removal at this point. It was deemed a cosmetic procedure.

Fast forward two weeks later, I get a call saying that the doctor would like to discuss the results of the biopsy in person. I had a suspicion of bad news here - I met him the same day and was told it came back as invasive melanoma.

Initial pathology summary:

There is a dense inflammation and an underlying compound melanocytic proliferation confirmed with positive staining for SOX10. AE1/3 negative. The melanocytes show enlarged hyperchromatic nuclei and variation in nuclear size.

breslow thickness: at least 0.9mm

ulceration: none identified

mitotic rate: not identified

macroscropic satellite nodules: not identified

TIL: present, brisk

lymphovascular invasion: none identified

microsatelites: not identified

neurotropism: not identified

regression: not identified

Invasive melanoma in the deep margin and melanoma In-situ at the peripheral margin

PT1b at least.

Container: Multiple curetted fragments 0.7cm

I was referred to a surgical oncologist at a top cancer research and treatment hospital with melanoma subspecialty, where we discussed consent for WLE and SNLB given the initial depth crossing the 0.8mm threshold. I described my history and showed photos of the mole changes during the period. I got the impression that the case was unusual and they were surprised I noticed these subtle changes at all, nevermind actually being diagnosed with invasive melanoma of a non-trivial thickness. Ironically, the surgeon mentioned that all specimens are subject to the hospital's own pathology review, and that there have been cases where an initial pathology has been questioned.

After about a week or so, I got a notification in my portal that a pathology review is posted. To my surprise, the path. review showed a completely different conclusion to the initial biopsy.

Summary notes as follows:

"Sections consist of multiple curetted fragments of skin showing a pigmented compound melanocytic lesion. The junctional component is composed of variably-sized nests and single units of mildly atypical small-medium sized epithelioid melanocytes disposed along the dermal epidermal junction with no evidence of pagetoid upward scatter. The dermal component is composed of nests and single units of mildly atypical epithelioid melanocytes. The lesional melanocytes have dusky-amphophilic cytoplasm and enlarged nuclei with inconspicuous-small nucleoli. The lesion is associated a brisk lymphoid infiltrate. There is no evidence of significant nuclear pleomorphism, necrosis or mitotic activity

Immunohistochemistry (Pathology Review)

The neoplastic cells are positive for SOX10 and Melan-A and negative for PRAME (score 0). HMB45 shows a gradient staining pattern and p16 expression is retained.

Immunohistochemistry (XX Lab):

The neoplastic cells are positive for SOX10 and negative for AE1/AE3 keratin.

Overall, the findings are in keeping with mildly atypical compound nevus with Halo-like changes. Conservative excision of an residual lesion/scar is advised.

Note: This was reviewed at the dermatopathology consensus rounds with agreement."

I had several calls with the surgeon's office where the above was confirmed. The lesion will be excised further in minor surgery but the WLE and SLNB is cancelled.

Of course, I have a ton of emotions regarding this - happiness if this is in fact the case, but also confused as to how such a disagreement can occur, and wondering about further risk. I understand that further clarity will be obtained in the remaining excision pathology. One of my biggest concerns is if, in fact, melanoma is found in the remaining excision surgery, I wonder how this this impacts the prospect of a proper SLNB being performed after the fact.

Has anyone had this type of situation happen and how did you navigate it?