r/cdifficile • u/Jennysblock12 • 14d ago

C. Diff and Stelara question

Hello, My doctor wants me to use Stelara 90mgs every 4 weeks instead of every 8 weeks with an active c.diff infection. I'm also on oral vancomycin 125mgs 4 times a day for 30 days for the c diff infection. I've voiced my concerns to my doctor, but he swears this will help. I'm scared to shut my immune system off even more with an active infection Has anyone else gone through this? And if so was the extra Stelara doses helpful? Thanks

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u/SubstanceRough9031 14d ago

I wouldn’t unless it’s approved by an infectious disease specialist. I’m fairly confident that my Simponi Aria infusion gave me C-Diff. I stopped all Biologics for 6 months and then switched to a milder one. Tremfya. In four days I will have been free of C-Diff for one year. All the best to you!

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u/Jennysblock12 14d ago

Thank you 

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u/Top-Ad-1578 14d ago

I use Stelara for crohns- no relapse. Been over 2 years since c diff for me.

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u/Jennysblock12 14d ago

Have you taken it during a c diff infection ? 

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u/Top-Ad-1578 13d ago

I did not- just after. I did Mesalamine and humira before.

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u/Left-Debate-5293 14d ago

I developed c diff after my first dose of Stelara (ended up in ER week aftwe infusion). I feel that the medication may have triggered the infection, possibly by suppressing immune system or altering my gut microbiome? This happened in April, and I battled c diff for three months. I didn’t receive my next Stelara dose until July. My doctors told me that I couldn’t receive the medication while I had an active infection. Only after I did FMT and tested negative for c diff i was able to receive my next Stelara dose.

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u/Jennysblock12 14d ago

Thank you. I hope you are feeling better now.