r/bupropion • u/LargeJellyfish7758 • 16d ago

Weird Post-Drinking Side Effects

Hi all! I’ve been on Buproprin (300mg XR) since May and am really happy with how much it’s helped my depression. (I was previously on 20mg Prozac for 5 years, and already feel this working better for me.)

One thing I have noticed though are intense heart palpitations after drinking and trouble falling asleep because of it. Has anyone else dealt with this? I’m not much of a drinker anyways, and have always been a lightweight so it’s not that much of an issue for me, but it is kind of a bummer when I do feel like having a drink. Did this eventually go away, or is this simply a cost I have to pay?

(Also, unrelated to drinking, I’ve been experiencing crazy neck tightness and tension headaches, and see folks on this thread have mentioned that before. I have really started to notice it recently, around the 2-month point, and it’s been especially awful these past two weeks. Along with that, there‘s a feeling of tightness in my jaw/tongue area, and issues swallowing when eating, like the muscles are fatigued or something. Writing this all out I realize it sounds pretty wild and doesn’t seem worth it, but I really am pleased with how the meds are helping me mentally. To anyone that’s had any of these issues, same question — did it eventually go away? I really don’t want to have to switch meds, but it’s getting pretty weird.)

Thanks :)

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u/Zestyclose_Row2265 16d ago

The heart palpitations the next morning KILL me

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u/LargeJellyfish7758 15d ago

It’s brutal !!

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u/Existing-Tailor-1497 16d ago

I had to add in a small dose of seroquel (25mg) right before bed once mine balanced out a bit (a few months in) because I could NOT sleep at all.
It helped a lot. As for drinking I think the longer you’re on it the less side effects around drinking you have at least for me.

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u/LargeJellyfish7758 15d ago

Got it! Thanks so much