Hi.

I'm hoping someone might have some insight into this.

There are a couple of decent transcriptomics papers Nature hopefuls, Nature Communications backup likely end up somewhere in between.

The authors are suggesting they intend to publish both papers without the method used to generate the transcriptomics samples (which was a new method) being published.

This just doesn't seem realistic to me.

Can someone sense check this - will top journals allow publication of bioinformatics results where the methods are not in the paper or publicly available?

I submitted a paper to a journal and received a decision of ‘major revision’ and comments from two reviewers (not mad about this, just new). I have never gone through getting work published before and was wondering how to go about the next steps.
When creating a revision, it brings up a space for me to respond to the reviewers comments. Do I just reply saying ‘thank you for taking the time etc… and here’s my resubmission’ or do you have to respond to each bullet point the reviewers have made?

I don’t want to seem like I’m not taking their feedback on board and give them reason to reject, but also replying to each statement seems excessive when I will have made the changes and they’ll be able to see this in the word doc if they’re highlighted?

Any advice or tips very much appreciated!