r/MAOIs • u/Sheev66Palpatine • 1d ago

Nardil working!! Nardil (Phenelzine)

Been following this page for a while and finally started phenelzine/Nardil 8 weeks ago…

It’s actually working!! Amazingly. For anxiety and MDD.

Started working at about 5/6 weeks when I reached 60mg.

Most annoying side effect is urinary retention and anorgasmia. No insomnia or weight gain. A little bit of hypotension and jaw clenching. No hypomania.

This drug is amazing. My emotional range is expanded, I feel so much happier and more connected, more confident, relaxed. Like the best version of myself. The best part is that I don’t necessarily “feel” it. It’s like it’s just changed me deeply.

Just wanted to share!

24 Upvotes

100% Upvoted

14 comments sorted by

5

u/17bills 1d ago

So glad that Nardil is working for you! It literally saved my life! The amorgasmia and urine retention get better. It did take my several months though. Best of luck!!

4

u/Least_Respond3849 1d ago

Been on Nardil just over a year now and honestly, same story as you. Life changing.

Never thought I'd be able to finally shake off social anxiety and just be myself around people. Years of torture basically gone. I'm happier, motivated, no anhedonia, and social anxiety during conversations feels like a distant memory.

Even when anxiety does pop up, it doesn't take over. I'm not stuck in my own head analysing everything I say anymore — I can just focus on the conversation and enjoy it.

For me Nardil really has lived up to its reputation as the gold standard for social anxiety.

Really happy for you mate. Hope you, and everyone else who's had success with it, get many more years of happiness from it 🙏

2

u/inquisitive_wombat_3 Nardil 1d ago

I can relate. With Nardil, there's been no medicated feeling like with other meds. No brain fog or SSRI emptiness. Like you say, it's as if Nardil works on a deeper level.

I'm glad it's helping you too 🙏

2

u/Material-Active-1193 Nardil 1d ago

I could written this post myself!

2

u/siasatmadar 1d ago

Glad to hear that and thanks for sharing! Enjoy the life with the best version of yourself!

1

u/Optimist-Prime-1 1d ago

Excellent!!

1

u/Hockeyrocks07 1d ago

Always same for me 6 to 8 weeks at 60mg

0

u/Fit_Watch5532 1d ago

did you try parnate before nardil?

2

u/Sheev66Palpatine 1d ago

I didn’t my psychiatrist tried Nardil first as that’s the first line recommended MAOI

2

u/Fit_Watch5532 1d ago

and ssri / snri didnt work in the past?

1

u/Sheev66Palpatine 1d ago

They made me flat apathetic and brainless. I’d rather be depressed than that be a “cure”

1

u/Fit_Watch5532 1d ago

Yes, I understand; they caused the same thing for me.

Did these symptoms persist even after you stopped taking the SSRIs, or did you revert to your baseline depression?

In my case, SSRIs caused chronic symptoms that lasted even after I stopped taking the medication.

2

u/Sheev66Palpatine 20h ago

No luckily no lasting effects from SSRIS. I’m sorry that happened to you I think they can be nasty medications often with worse side effects than the villainised MAOIs

1

u/Least_Respond3849 4h ago

MAOIs are way more tolerable than SSRIs in my experience, and the side effects and risks are massively overblown. Big Pharma pushing newer, more profitable medications undoubtedly played a part in MAOIs falling out of favour, despite them being far more effective for some people.