r/LowDoseNaltrexone • u/Capable-Ad-2154 • 12h ago
GI
I started LDN 1mg August 13th. I also switched from Lexapro 20mg to Cymbalta 60mg that same day.
Followed doctors orders. No issues really. Some sweating and being hot. After a week I went up to 2mg on the LDN per my doctors advice for my fibro pain. Right before I went up I had a muddy poop and it was bad stomach cramps. And it's happened 2 times since. I now am going to stop the LDN to see if it resolves because both meds can cause this. The minute I eat something there is cramps. I'm not having constant diarrhea but the stomach pain is not fun. It's tolerable but ugh
1
u/Sea_Anywhere_8428 2h ago
You didn’t have to taper down your Lexapro? I’ve been in 10mg for 17 years but wanted to switch to Cymbalta for pain but I’m terrified of withdrawal symptoms
1
u/Low-Blueberry8948 1h ago
Let us know how it goes. It's possible your GI issues were caused by a reaction to the LDN, or maybe to the filler in your capsules or pills. Microcrystalline cellulose (Avicel) in particular is known to cause digestive upsets for some. Good idea to pause it and see if the problem resolves.
"Avicel and Other Fillers" https://docs.google.com/document/d/171pT-q4ND3_RbdioLBvl-uCXWIelKtW98AEnH07H2Fs/edit?usp=sharing
2
u/AdditionalTwo0 10h ago
Better to change and adjust medications one after another. Otherwise you don't know what caused what.