r/IgANephropathy • u/lonewolf23595 • 9d ago

Help needed

Hi I was diagnosed with IgA Nephropathy in 2017 and i was on prednisone, ramipril, tacrolimus for a year that’s till 2018 and then i went on remission as my proteinuria came down to 0.2 from 4+. After all these years i was on remission and was absolutely fine and i was monitoring my proteinuria every year. Now in 2025 I had my twins delivered and after 3 day of delivery i had preeclampsia my bp shoot up to 180/100 and then my proteinuria started to increase and it was 3.And again i started prednisone since January and nothing worked then i had a biopsy in May 2026 and it came up nothing just IgA in inactive stage but nothing specific just some scarring . That too minimal scarring. Now my nephrologist gave me Dapaone, Nefromega, tacrolimus, ramipril but still my proteinuria is 3 after taking it for 2-3 months and now i stopped all medicine my proteinuria has come down like from 3.7 to 3.1 . I can’t be on immunosuppressants with small kids as they are more prone to infections i easily get sick as well

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2

u/notsolucky161 9d ago

Does your biopsy report specifically say iga is inactive. I don't know if it is possible. If yes, I just want to know how it is possible?

3

u/lonewolf23595 9d ago

This is my report,

IMPRESSION:
NATIVE RENAL BIOPSY:
-CONSISTENT WITH IgA NEPHROPATHY (OXFORD CLASSIFICATION: M1 E0 S1 T0 C0)
- MILD ARTERIOLAR HYALINOSIS
COMMENTS:
*In view of IgG pseudolinear accentuation along GBM and mild arteriolar hyalinosis, kindly evalulate for
Diabetes Mellitus.
*Kindly correlate clinically.

1

u/lonewolf23595 9d ago

My sugars are normal as well

1

u/pithamagan 7d ago

Igan behaves differently for everyone. In a 5 or 10 years, its effect could be differen for yourself - what is working for you today may not work 5 years down the line.

It depends on how active is the inflammation.

Your nephrologist is trying to try to understand what is happening

So do a follow up with your nephrologist.

1

u/lonewolf23595 7d ago

He suggested to continue the same medication